NASDAQ Framework: SpringWorks Therapeutics Inc.
Biopharmaceutical company focused on rare diseases 1.
1: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source
SpringWorks Therapeutics, Inc., headquartered in Stamford, Connecticut, is a commercial-stage biopharmaceutical company dedicated to developing and commercializing medicines for underserved patient populations suffering from rare diseases and cancer. The company's lead product candidates include OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor in Phase III trials for desmoid tumors, and mirdametinib, an oral small molecule MEK inhibitor in Phase 2b trials for neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN). Additionally, SpringWorks is advancing other therapies through various clinical stages, including combination treatments for genetically defined solid tumors. The company collaborates with notable entities such as BeiGene, Ltd., GlaxoSmithKline LLC, and Pfizer Inc., and holds several license agreements to support its innovative pipeline 2.
2: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source
UNKNOWN
The available facts do not provide information about whether the founders of SpringWorks Therapeutics Inc. are still leading the company or are heavily involved in its operations.
The available facts do not provide information about whether the founders of SpringWorks Therapeutics Inc. are still leading the company or are heavily involved in its operations.
MEDIUM RISK
SpringWorks Therapeutics Inc. is actively developing and commercializing multiple therapies, including OGSIVEO (nirogacestat) and mirdametinib, which are in advanced clinical stages 3. The company has also achieved significant milestones such as FDA approval for OGSIVEO and the submission of a New Drug Application for mirdametinib 45. However, insider trading activities, such as the sale of shares by the CEO and other executives, might indicate potential concerns about the company's future performance 6789. Additionally, while the company has raised funds through public offerings 10, the lack of detailed financial metrics such as profitability and debt levels makes it challenging to assess the overall financial health comprehensively. Therefore, the financial situation of SpringWorks Therapeutics Inc. can be considered as medium risk.
SpringWorks Therapeutics Inc. is actively developing and commercializing multiple therapies, including OGSIVEO (nirogacestat) and mirdametinib, which are in advanced clinical stages 3. The company has also achieved significant milestones such as FDA approval for OGSIVEO and the submission of a New Drug Application for mirdametinib 45. However, insider trading activities, such as the sale of shares by the CEO and other executives, might indicate potential concerns about the company's future performance 6789. Additionally, while the company has raised funds through public offerings 10, the lack of detailed financial metrics such as profitability and debt levels makes it challenging to assess the overall financial health comprehensively. Therefore, the financial situation of SpringWorks Therapeutics Inc. can be considered as medium risk.
3: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source4: SpringWorks Therapeutics Completes Submission of New Drug Application to the FDA for Mirdametinib for the Treatment of Children and Adults with NF1-PN View Source5: SpringWorks Therapeutics Reports First Quarter 2024 Financial Results and Highlights Recent Business Updates View Source6: Almost all investors and traders prefer to invest in shares controlled by the management of a corporation as a management company will be more likely to run the business itself and to never conduct things against the management’s desires and will always try to do what is best for their shareholders. Currently, 11.66 percent of SpringWorks Therapeutics Inc shares are owned by insiders, and 98.73 percent are held by financial institutions. Islam Saqib, the Chief Executive Officer at SpringWorks Therapeutics Inc (SWTX) has sold 49,000 shares of firm on Jun 03 ’24 at a price of $39.90 against the total amount of $1.96 million. In another inside trade, Edris Badreddin, Chief Operating Officer of SpringWorks Therapeutics Inc (NASDAQ:SWTX) sold 20,000 shares of the firm on Jun 03 ’24 for a total worth of $0.8 million at a price of $40.07. An inside trade which took place on Jun 03 ’24, Director of SpringWorks Therapeutics Inc Hambleton Julie sold 4,648 shares of firm against total price of $0.19 million at the cost of $40.03 per share. View Source7: Insider Sale: Director Julie Hambleton Sells Shares of SpringWorks Therapeutics Inc (SWTX) View Source8: Insider Sale: COO Badreddin Edris Sells 20,000 Shares of SpringWorks Therapeutics Inc (SWTX) View Source9: Insider Sale: CEO Saqib Islam Sells 49,000 Shares of SpringWorks Therapeutics Inc (SWTX) View Source10: Ventyx Biosciences Inc VTYX Allakos Inc ALLK SpringWorks Therapeutics Inc Ordinary Shares SWTX View Source
NO
There is no evidence in the provided facts indicating that SpringWorks Therapeutics Inc. is launching any new product offerings. The facts primarily discuss ongoing clinical trials, regulatory submissions, and financial updates.
There is no evidence in the provided facts indicating that SpringWorks Therapeutics Inc. is launching any new product offerings. The facts primarily discuss ongoing clinical trials, regulatory submissions, and financial updates.
SpringWorks Therapeutics Inc. has outlined a robust product roadmap and expansion strategy for 2024 through 2026, focusing on advancing its lead product candidates and expanding its clinical pipeline. The company is progressing with OGSIVEO (nirogacestat), which has received FDA approval for desmoid tumors and is in Phase 2 clinical development for ovarian granulosa cell tumors 11. Additionally, SpringWorks has completed the submission of a New Drug Application for mirdametinib for treating neurofibromatosis type 1-associated plexiform neurofibromas (Nf44871-PN) 12. The company is also exploring combination therapies and other monotherapy approaches for various genetically defined solid tumors, including low-grade gliomas 13. Collaborations with industry leaders such as BeiGene, GlaxoSmithKline, and Pfizer further bolster its innovative pipeline and strategic growth 14.
11: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source12: SpringWorks Therapeutics Completes Submission of New Drug Application to the FDA for Mirdametinib for the Treatment of Children and Adults with NF1-PN View Source13: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source14: SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut. View Source